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Micro-manipulation

It is a technique for fine manipulation of tiny organisms or substances under a microscope and is widely used in cell biology, embryology, genetics and other fields. It is mainly performed by means of high-precision robotic arms or micromanipulators, for example, to inject, isolate, transplant or manipulate tiny particles of individual cells. Inverted microscopes are often used in conjunction with micromanipulation equipment, and due to their long working distance and flexible viewing angle, they are able to perform precise manipulation while maintaining sample stability. This technology plays an important role in biological research, genetic engineering and medical applications such as in vitro fertilization and stem cell injections.

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1

Main application areas of micromanipulation

Microinjection is used to inject DNA, RNA, or proteins into cells to support gene editing, in vitro fertilization, and monosperm injections; micromanipulation is also used for cell manipulation, cloning experiments, microdissection, and nanotechnology, advancing genetic, pathology, and materials science.

2

Difference between microscopic operation microscope and ordinary inverted fluorescence microscope

The main difference lies in its high-precision micro-manipulation system, Hoffman-modulated contrast imaging and precise temperature control system, which are suitable for precise manipulation of tiny samples, whereas ordinary inverted fluorescence microscopes are mainly used for fluorescence imaging and observation, and are not equipped with these manipulation functions.

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What are the common brands of micromanipulation?

Common micromanipulation brands include Narishige from Japan, Sutter Instruments from the U.S. and Eppendorf from Germany. Domestic brands such as Sunny Instruments can also provide a full set of micromanipulation solutions, covering the complete configuration from micro-manipulation system to micro-imaging, demonstrating the rapid development of domestic equipment in the field of precision manipulation.

Excellent optical performance

This microscope features an excellent optical system that supports observation methods like phase contrast, Hoffman modulation contrast, and DIC, enhancing sample contrast and revealing minute cellular structures.

With high-quality objectives, it offers high resolution for detailed imaging of live cell dynamics or static sample structures, ensuring exceptionally clear results.

More Precise and Efficient Operating Experience

The three-axis electric control system allows micron-level adjustments in the X, Y, and Z axes for accurate sample handling.

Its flexible design adapts to various experimental needs, while powerful software enables data recording, automation, and parameter adjustments, streamlining processes and minimizing errors for long, precise experiments.

Complete Temperature Control System

The microscope's stage temperature control system precisely maintains physiological temperatures (e.g., 37°C) for sensitive samples like cells and embryos.

With quick response and stability, it prevents fluctuations that could harm samples or affect results, making it ideal for high-requirement applications like in vitro fertilization (IVF).